Food reduces the absorption of imidapril and moexipril, and reduces the conversion of perindopril to its active metabolite, perindoprilat.
It is recommended that imidapril and perindopril should be given before food. The US manufacturers suggest taking moexipril one hour before food, although the interaction is of doubtful clinical significance. Food has little or no clinically important effect on the absorption of captopril, cilazapril, enalapril, fosinopril, lisinopril, moexipril, quinapril, ramipril, spirapril, and trandolapril.
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