5-HT3-RECEPTOR ANTAGONISTS AND SSRIS

Symptoms similar to serotonin syndrome have been reported in two patients receiving paroxetine and ondansetron or sertraline and dolasetron.
It has been suggested that that a variant of serotonin syndrome, may rarely be seen when 5-HT3-receptor antagonists and SSRIs are given together, and clinicians should consider this possibility if both drugs are given.
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