HYOSCYAMINE, METHENAMINE, METHYLENE BLUE, AND PHENYL SALICYLATE

(HYE oh SYE a meen, meth EN a meen, METH il een BLUE, FEEN il sa LIS il ate) Brand: Darpaz, Hyophen, Phosphasal, Prosed/DS, Urelle, Uribel, Uro Blue, Ustell, Uta, UTICAP, Utira, Utira-C

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What is the most significant information I must know about this medication?

• You must not use this medication if you are allergic to hyoscyamine, methenamine, methylene blue, or phenyl salicylate.

• Till taking this medicine, speak your doctor if you have any type of heart problem (congestive heart failure, coronary heart malady, a heart valve or heart rhythm disorder), glaucoma, an enlarged prostate, bladder obstruction, myasthenia gravis, a stomach ulcer or obstruction, or if you are allergic to belladonna (Donnatal and others).

• Drink plenty of liquids while you are taking this medication.

• Much drugs can interact with this medication. Also, hyoscyamine can create it harder for your body to absorb another medications you take by mouth. Tell your doctor about all your medications and any you start or stop using.

• If you have an eye exam and your pupils are dilated with eye drops, speak the eye doctor onward of time that you are using hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

What is hyoscyamine, methenamine, methylene blue, and phenyl salicylate?

Hyoscyamine produces much effects in the body, including relief from muscle spasms.

Methenamine and methylene blue work as mild antiseptics that fight bacteria in the urine and bladder.

• Phenyl salicylate is a mild pain reliever.

Hyoscyamine, methenamine, methylene blue, and phenyl salicylate is a combination medication used to treat bladder irritation (pain, burning, inflammation) caused by urinary tract infection. This medicine is also used to prevent bladder discomfort during a medical procedure.

Hyoscyamine, methenamine, methylene blue, and phenyl salicylate may also be used for purposes not listed in this medicine guide.

What must I discuss with my healthcare provider till taking this medication?

• You must not use this medication if you are allergic to hyoscyamine, methenamine, methylene blue, or phenyl salicylate.

• To create certain this medication is safety for you, speak your doctor if you have:

· heart disease;

· a heart rhythm disorder;

· congestive heart failure;

· coronary heart disease;

· a heart valve disorder;

· glaucoma;

· an enlarged prostate or bladder obstruction;

· myasthenia gravis;

· an ulcer or obstruction in your stomach; or

· if you are allergic to belladonna (Donnatal and others).

• FDA pregnancy category C. It is not known whether this medicine will harm an unborn child. Speak your doctor if you are pregnant or plan to become pregnant while using this medication.

Hyoscyamine, methenamine, methylene blue, and phenyl salicylate can pass into breast milk and may harm a nursing child. Speak your doctor if you are breast-feeding a baby.

• This medication must not be given to a baby younger than 7 years old.

• Older adults may be more likely to have side effects from this medication.

How must I take this medication?

Hyoscyamine, methenamine, methylene blue, and phenyl salicylate is generally taken 4 times daily. Follow all directions on your prescription label. Do not take this medication in larger or less amounts or for longer than recommended.

Do not crush, chew, or interrupt an enteric coated pill. Swallow it intact. The pill has a particular coating to protect your stomach. Breaking the pill will hurt this coating.

• Drink plenty of liquids while you are taking this medication.

• If you have an eye exam and your pupils are dilated with eye drops, speak the eye doctor onward of time that you are using hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

• Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

• Take the missed doze as soon as you remember. Skip the missed doze if it is nearly time for your following scheduled doze. Do not take extra medication to create up the missed dose.

What happens if I overdose?

• Search abnormal medical attention or call the Poison Help line at 1-800-222-1222.

What must I avoid while taking this medication?

• Avoid taking an antacid or anti-diarrhea medication within 1 hour till or after you take hyoscyamine, methenamine, methylene blue, and phenyl salicylate. Antacids or anti-diarrhea medication can create it harder for your body to absorb hyoscyamine.

• If you also take ketoconazole (Nizoral), wait at least 2 hours after taking it till you take hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

What are the possible side effects of hyoscyamine, methenamine, methylene blue, and phenyl salicylate?

Methylene blue will most likely reason your urine or stools to appear blue or green in color. This is a usual side effect of the medicine and will not reason any harm.

• Get abnormal medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your person, lips, tongue, or throat.

• Stop using this medicine and call your doctor at once if you have:

· severe dizziness, blurred vision, quick heart rate;

· agitation, confusion, feeling restless or excited;

· painful or difficult urination; or

· feeling short of breath.

• General side effects may include:

· mild dizziness;

· drowsiness; or

· flushing (warmth, redness, or tingly feeling).

• This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may message side effects to FDA at 1-800-FDA-1088.

What another drugs will affect hyoscyamine, methenamine, methylene blue, and phenyl salicylate?

• Much drugs can interact with this medication. Not all possible interactions are listed here. Also, hyoscyamine can create it harder for your body to absorb another medications you take by mouth. Tell your doctor about all your medications and any you start or stop using, especially:

· neostigmine, pyridostigmine;

· bladder or urinary medicines such as darifenacin, fesoterodine, oxybutynin, tolterodine, solifenacin;

· bronchodilators such as ipratropium or tiotropium;

· cool or allergy medication that contains an antihistamine;

· a diuretic or "water pill";

· an MAO inhibitor--furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, tranylcypromine;

· medicine to treat excess stomach acid, stomach ulcer, motion sickness, or irritable bowel syndrome;

· medicine to treat gout, kidney stones, or an electrolyte imbalance (such as low levels of potassium);

· medicine to treat symptoms of Alzheimer's malady or Parkinson's disease;

· narcotic pain or cough medication--codeine, fentanyl, hydrocodone, hydromorphone, methadone, morphine, oxycodone, propoxyphene, and others; or

· sulfa drugs.

This list is not complete and much another drugs can interact with hyoscyamine, methenamine, methylene blue, and phenyl salicylate. This includes prescription and over-the-counter medicines, vitamins, and herbal commodity. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

• Your pharmacist can provide more information about hyoscyamine, methenamine, methylene blue, and phenyl salicylate.

Remember, hold this and all another medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Disclaim: Each effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses external of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way must be construed to indicate that the drug or drug combination is safety, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the help of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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