DIGOXIN AND DIURETICS - LOOP OR THIAZIDE DIURETICS

Hypokalaemia, which can be caused by potassium-depleting diuretics such as the loop or thiazide diuretics, increases the toxicity of digoxin.
Potassium levels should be routinely monitored during diuretic therapy. However, if symptoms of digoxin toxicity occur (see above) it may be prudent to re-check potassium levels.
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