COLESTYRAMINE AND RELATED DRUGS AND VANCOMYCIN

Colestyramine binds to vancomycin in the gut, possibly reducing its efficacy.
Administration of oral vancomycin and colestyramine should be separated (it is usually suggested that other drugs should be given 1 hour before or 4 to 6 hours after colestyramine). Note that this combination is no longer recommended in antibiotic-associated colitis.
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