CHLOROQUINE AND PENICILLAMINE

The concurrent use of chloroquine and penicillamine may result in increased toxicity, possibly as a result of increased penicillamine levels.
If problems occur consider this drug interaction as a possible cause. Note that chloroquine, hydroxychloroquine and penicillamine are associated with serious haematological adverse effects, and therefore the US manufacturers suggest that the use of penicillamine with either of these drugs should be avoided.
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