Apo-Bisacodyl , Bisacolax, Bisco-Lax , Dacodyl, Deficol, , Doxidan, Dulcolax, Fleet Bisacodyl, Laxit , Theralax
Classifications: stimulant laxative; Therapeutic: laxative
Pregnancy Category: C
5 mg tablets, enteric coated; 5 mg tablet, delayed release; 10 mg suppository; 10 mg/30 mL enema
Expands intestinal fluid volume by increasing epithelial permeability.
Induces peristaltic contractions by direct stimulation of sensory nerve endings in the colonic wall.
Temporary relief of acute constipation and for evacuation of colon before surgery, proctoscopic, sigmoidoscopic, and radiologic
examinations. Also used to cleanse colon before delivery and to relieve constipation in patients with spinal cord damage.
Acute surgical abdomen, nausea, vomiting, abdominal cramps, intestinal obstruction, fecal impaction; use of rectal suppository
in presence of anal or rectal fissures, ulcerated hemorrhoids, proctitis, bowel obstruction or perforation, ileus; pregnancy
(category C), children <1 y.
Route & Dosage
Adult: PO 515 mg prn (max: 30 mg for special procedures) PR 10 mg prn
Child: PO ≥6 y, 510 mg prn PR ≥2 y, 10 mg; <2 y, 5 mg
- Give in the evening or before breakfast because of action time required.
- Give enteric coated tablets whole to avoid gastric irritation; do not cut or crush. Patient should not chew tablets. Preferably
give with a full glass (240 mL) of water or other liquid.
- Do not give within 1 h of antacids or milk. These substances may cause premature dissolution of enteric coating; early release
of drug in stomach may result in gastric irritation and loss of cathartic action.
- Store tablets in tightly closed containers at temperatures not exceeding 30° C (86° F).
- Suppository may be inserted at time bowel movement is desired.
- Storage is same as tablets.
Adverse Effects (≥1%)
Systemic effects not reported. Mild cramping, nausea, diarrhea, fluid and electrolyte disturbances (especially potassium
will cause early dissolution of enteric
coated tablets, resulting in abdominal cramping.
515% from GI tract. Onset:
68 h PO; 1560 min PR. Metabolism:
In liver. Elimination:
In urine, bile, and breast milk.
Assessment & Drug Effects
- Evaluate periodically patient's need for continued use of drug; bisacodyl usually produces 1 or 2 soft formed stools daily.
- Monitor patients receiving concomitant anticoagulants. Indiscriminate use of laxatives results in decreased absorption of
Patient & Family Education
- Add high-fiber foods slowly to regular diet to avoid gas and diarrhea. Adequate fluid intake includes at least 68