The blood levels of metoprolol are increased in women taking hormonal contracep- tives, but the
clinical importance of this is probably very small. Acebutolol, oxprenolol and propranolol
pharmacokinetics are minimally affected by
contraceptives.
No action needed. However, be aware that hormonal
contraceptives are cautioned or contraindicated in some of the patient groups who may be treated with beta blockers, and oestrogens can raise blood pressure, which may antagonise the effects of the
beta blockers.